SCHEMBL9116375

SCHEMBL9116375

C=C/C=C(/C(=O)O)c1sccc1C#N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
POLB P06746 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
KMT2A Q03164 6/20 0.34
MEN1 O00255 5/20 0.34
HPGD P15428 1/20 0.34
BLM P54132 1/20 0.34
KDM4E B2RXH2 4/20 0.34
ALDH1A1 P00352 3/20 0.34
KDM4C Q9H3R0 1/20 0.34
MAPT P10636 3/20 0.32
ALOX15 P16050 2/20 0.32
USP2 O75604 1/20 0.32
CASP7 P55210 1/20 0.32
HSD17B10 Q99714 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9116385 1.00 LMNA (0.36) LMNANPSR1POLBRAB9ASMN1; SMN2
SCHEMBL4949422 0.75 LMNA (0.43) LMNANPSR1POLBRAB9ASMN1; SMN2
SCHEMBL3935182 0.72 POLB (0.38) LMNANPSR1POLBRAB9AHPGD
SCHEMBL3935191 0.72 POLB (0.38) LMNANPSR1POLBRAB9AHPGD
SCHEMBL24577695 0.70 LMNA (0.39) LMNANPSR1POLBRAB9ASMN1; SMN2
SCHEMBL3056218 0.70 KDM4E (0.42) LMNANPSR1POLBRAB9ASMN1; SMN2
SCHEMBL506452 0.70 KDM4E (0.41) LMNANPSR1POLBRAB9ASMN1; SMN2
SCHEMBL27746186 0.68 CA2 (0.47) LMNARAB9AKMT2AMEN1KDM4E
SCHEMBL9117060 0.67 DAO (0.53) LMNAPOLBRAB9ASMN1; SMN2KMT2A
SCHEMBL12622649 0.67 POLB (0.52) LMNANPSR1POLBRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5424164-A Image forming method FUJI PHOTO FILM CO., LTD (JP) 1995-06-13 US disclosed