Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119044 | 0.90 | KIF11 (0.38) | KIF11PPARDPTGS2CTSKRORC | |
| SCHEMBL9116165 | 0.89 | KIF11 (0.44) | KIF11PPARDPTGS2LTA4HALOX5AP | |
| SCHEMBL8974709 | 0.86 | PTGS2 (0.42) | KIF11PTGS2CTSKLOXL2ALOX5AP | |
| SCHEMBL8975024 | 0.81 | PTGS2 (0.38) | KIF11PTGS2CTSKLOXL2ALOX5AP | |
| SCHEMBL9117083 | 0.79 | KIF11 (0.43) | KIF11PTGS2ALOX5APFEN1 | |
| SCHEMBL9117872 | 0.77 | HTR2A (0.45) | PTGS2CTSKRORC | |
| SCHEMBL9116856 | 0.76 | HTR2A (0.38) | PTGS2 | |
| SCHEMBL8974062 | 0.73 | KIF11 (0.45) | KIF11PTGS2ALOX5APFEN1 | |
| SCHEMBL9118890 | 0.73 | PTGS2 (0.48) | KIF11PTGS2CTSKALOX5APFEN1 | |
| SCHEMBL8973745 | 0.72 | POLB (0.39) | KIF11PTGS2CTSKLOXL2ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030656-A1 | SUBSTITUTED CYCLOPENTADIENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-11-16 | — | — | WO | disclosed |