SCHEMBL9116591

SCHEMBL9116591

CSc1ncccc1-c1oncc1C(=O)C1CC1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.41
ALDH1A1 P00352 4/20 0.39
KMT2A Q03164 6/20 0.38
MEN1 O00255 4/20 0.38
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.36
NPC1 O15118 1/20 0.36
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
CASP3 P42574 2/20 0.34
SENP8 Q96LD8 2/20 0.34
SENP7 Q9BQF6 2/20 0.34
SENP6 Q9GZR1 2/20 0.34
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.34
USP2 O75604 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9117857 0.81 L3MBTL1 (0.36) RAB9AALDH1A1KMT2AMEN1LMNA
SCHEMBL8100428 0.74 ALDH1A1 (0.33) ALDH1A1KMT2AMEN1LMNA
SCHEMBL8108797 0.74 HCRTR1 (0.37) RAB9AALDH1A1KMT2ALMNANPC1
SCHEMBL8114341 0.72 PDE4A (0.40) KMT2AMEN1LMNATSHR
SCHEMBL9119031 0.72
SCHEMBL8906973 0.72 HPGD (0.36) RAB9AALDH1A1KMT2AMEN1LMNA
SCHEMBL8725745 0.71 HCRTR1 (0.34) ALDH1A1KMT2ALMNAGAA
SCHEMBL7700504 0.71 RAB9A (0.48) RAB9AALDH1A1KMT2AMEN1LMNA
SCHEMBL8726295 0.71 MELK (0.36) RAB9AALDH1A1NPC1
SCHEMBL8041945 0.70 AR (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995025099-A1 2-CYANO-1,3-DIONE DERIVATIVES USEFUL AS HERBICIDES RHONE-POULENC AGRICULTURE LTD. (GB) 1995-09-21 WO disclosed