SCHEMBL9116930

SCHEMBL9116930

COc1cc2ncsc2cc1SC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.56
ATM Q13315 1/20 0.56
L3MBTL1 Q9Y468 4/20 0.45
LMNA P02545 3/20 0.45
MAPT P10636 3/20 0.45
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 2/20 0.45
HTT P42858 2/20 0.45
GAA P10253 1/20 0.45
HPGD P15428 1/20 0.45
MAPK1 P28482 1/20 0.45
RECQL P46063 1/20 0.45
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
THRB P10828 1/20 0.41
PTK6 Q13882 1/20 0.39
STING1 Q86WV6 2/20 0.35
POLB P06746 1/20 0.35
NPC1 O15118 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4046681 0.82 ALDH1A1 (0.39) ALOX15ATML3MBTL1KDM4EALDH1A1
SCHEMBL30702433 0.82 PTK6 (0.41) L3MBTL1LMNAMAPTKDM4EALDH1A1
SCHEMBL927420 0.82 PTK6 (0.41) L3MBTL1LMNAMAPTKDM4EALDH1A1
SCHEMBL9116750 0.77 TRPM5 (0.37) ALOX15ATML3MBTL1MAPTKDM4E
SCHEMBL9117370 0.77 TGFBR1 (0.35) ALOX15ATML3MBTL1KDM4EALDH1A1
SCHEMBL5080801 0.77 PTK6 (0.39) ALOX15ATML3MBTL1LMNAMAPT
SCHEMBL19435584 0.76 PTK6 (0.46) L3MBTL1LMNAMAPTKDM4EALDH1A1
SCHEMBL8567994 0.76 NPC1 (0.44) MAPTKDM4EALDH1A1GAAHPGD
SCHEMBL9117566 0.74 P2RX7 (0.40) L3MBTL1LMNAMAPTKDM4EALDH1A1
SCHEMBL29534681 0.72 PTK6 (0.46) L3MBTL1LMNAMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5387502-A Containing specified cyanine dye sensitizer; high sensitivity, storage stability FUJI PHOTO FILM CO., LTD. (JP) 1995-02-07 US disclosed