Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 11/20 | 0.52 |
| ▸ | IDH2 | P48735 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118064 | 0.94 | PTGES (0.50) | RAF1IDH2BRAFPTGESALOX5 | |
| SCHEMBL9118546 | 0.91 | RAF1 (0.52) | RAF1BRAFPTGESALOX5P2RY1 | |
| SCHEMBL8432579 | 0.88 | PTGES (0.58) | IDH2PTGESALOX5 | |
| SCHEMBL8433479 | 0.87 | PTGES (0.49) | RAF1IDH2BRAFPTGESALOX5 | |
| SCHEMBL9117651 | 0.85 | HTT (0.56) | CYP2C9 | |
| SCHEMBL9116337 | 0.84 | P2RY1 (0.45) | P2RY1IDO1 | |
| SCHEMBL9117910 | 0.84 | PTGES (0.46) | IDH2PTGESALOX5P2RY1 | |
| SCHEMBL8432745 | 0.84 | PTGES (0.48) | BRAFPTGESALOX5 | |
| SCHEMBL9243116 | 0.82 | IDH2 (0.46) | RAF1IDH2BRAFP2RY1CYP2C9 | |
| SCHEMBL9289620 | 0.80 | PTGES (0.49) | RAF1IDH2PTGESALOX5CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033458-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | claimed |
| WO-1995033458-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |