Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | RAF1 | P04049 | 5/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118064 | 0.87 | PTGES (0.50) | IDH2HTTKMT2AMEN1MAPT | |
| SCHEMBL8740768 | 0.85 | KDR (0.50) | RAF1BRAF | |
| SCHEMBL9117246 | 0.82 | RAF1 (0.52) | IDH2RAF1BRAFCYP2C9IDO1 | |
| SCHEMBL9118596 | 0.81 | GRIK1 (0.49) | IDH2HTTKMT2AMEN1MAPT | |
| SCHEMBL8432579 | 0.81 | PTGES (0.58) | IDH2HTTKMT2AMEN1MAPT | |
| SCHEMBL9116521 | 0.79 | KMT2A (0.42) | HTTKMT2AMEN1MAPTCYP1A2 | |
| Diphenylmethanol SCHEMBL9188471 | 0.79 | GRIK1 (0.45) | IDH2HTTKMT2AMEN1MAPT | |
| SCHEMBL8433479 | 0.78 | PTGES (0.49) | IDH2HTTKMT2AMEN1MAPT | |
| SCHEMBL9119780 | 0.78 | L3MBTL1 (0.43) | IDH2HTTKMT2AMEN1MAPT | |
| SCHEMBL5719998 | 0.78 | CA12 (0.47) | IDH2HTTKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033458-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |