Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 5/20 | 0.45 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118064 | 0.90 | PTGES (0.50) | LMNAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL9117910 | 0.89 | PTGES (0.46) | P2RY1LMNAPOLBGAACA12 | |
| SCHEMBL9119349 | 0.85 | LMNA (0.54) | LMNAPOLBGAAALDH1A1KMT2A | |
| SCHEMBL9117246 | 0.84 | RAF1 (0.52) | P2RY1IDO1 | |
| SCHEMBL8432579 | 0.84 | PTGES (0.58) | LMNAGAACA12CA1CA2 | |
| SCHEMBL8433479 | 0.81 | PTGES (0.49) | LMNACA12CA1CA2CA9 | |
| SCHEMBL9118546 | 0.80 | RAF1 (0.52) | P2RY1GAAKMT2AMEN1MAPT | |
| SCHEMBL9117651 | 0.78 | HTT (0.56) | LMNAPOLBGAAALDH1A1KMT2A | |
| SCHEMBL9243116 | 0.77 | IDH2 (0.46) | P2RY1IDO1LMNAKMT2AMEN1 | |
| SCHEMBL8432745 | 0.76 | PTGES (0.48) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033458-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | claimed |
| WO-1995033458-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |