Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470966 | 0.86 | BACE1 (0.38) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL7470648 | 0.84 | PDK2 (0.41) | LMNAMAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL9116067 | 0.81 | MCL1 (0.44) | LMNAMAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL18529866 | 0.78 | ABL1 (0.49) | LMNAMAPTKDM4EALDH1A1GAA | |
| SCHEMBL7471683 | 0.75 | MAPK1 (0.34) | LMNAMAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL4072002 | 0.75 | ALDH1A1 (0.50) | LMNAMAPTKDM4EALDH1A1GAA | |
| SCHEMBL7464408 | 0.72 | TDP1 (0.40) | LMNAMAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL6185512 | 0.72 | CHEK1 (0.43) | LMNAMAPK1MAPTKDM4EALDH1A1 | |
| SCHEMBL1976165 | 0.72 | ABL1 (0.44) | LMNAMAPTKDM4EALDH1A1GAA | |
| SCHEMBL523584 | 0.72 | ABL1 (0.57) | LMNAMAPTKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025105-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD (GB) | 1995-09-21 | — | — | WO | disclosed |