Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.39 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | BCKDK | O14874 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464408 | 0.85 | TDP1 (0.40) | MCL1MAPK1MAPTTDP1BCL2L1 | |
| Hydrochloric Acid SCHEMBL7471693 | 0.84 | TDP1 (0.39) | MCL1MAPK1MAPTTDP1BCL2L1 | |
| SCHEMBL9117375 | 0.81 | LMNA (0.39) | MAPK1MAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL18529850 | 0.77 | TDP1 (0.52) | MAPTTDP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7471683 | 0.77 | MAPK1 (0.34) | MCL1MAPK1MAPTTDP1BCL2L1 | |
| SCHEMBL17063591 | 0.74 | ALDH1A1 (0.61) | MAPTTDP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11804008 | 0.73 | MCL1 (0.46) | MCL1MAPK1MAPTSTING1ALDH1A1 | |
| SCHEMBL6924772 | 0.73 | TDP1 (0.51) | MAPTTDP1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL18542613 | 0.73 | TDP1 (0.47) | MAPK1MAPTTDP1ALDH1A1KDM4E | |
| SCHEMBL2817995 | 0.73 | TDP1 (0.66) | MAPK1MAPTTDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025105-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD (GB) | 1995-09-21 | — | — | WO | disclosed |