Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CDC7 | O00311 | 2/20 | 0.32 |
| ▸ | PLK4 | O00444 | 2/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464408 | 0.88 | TDP1 (0.40) | MAPK1TSHRHTTSTING1MAPT | |
| SCHEMBL7470966 | 0.87 | BACE1 (0.38) | NPSR1MAPTKDM4EALDH1A1GSK3B | |
| Hydrochloric Acid SCHEMBL7471693 | 0.87 | TDP1 (0.39) | MAPK1TSHRHTTSTING1MAPT | |
| SCHEMBL9239722 | 0.79 | ALDH1A1 (0.38) | TSHRNPSR1STING1MAPTKDM4E | |
| SCHEMBL7466991 | 0.78 | DYRK1A (0.32) | MAPK1STING1MAPTKDM4EALDH1A1 | |
| SCHEMBL9116067 | 0.77 | MCL1 (0.44) | MAPK1PRNPTSHRPPARGHTT | |
| SCHEMBL11281015 | 0.76 | ALDH1A1 (0.38) | MAPK1HTTNPSR1MAPTKDM4E | |
| SCHEMBL9117375 | 0.75 | LMNA (0.39) | MAPK1PRNPTSHRPPARGHTT | |
| SCHEMBL7469350 | 0.73 | DHODH (0.31) | RAB9ANPC1 | |
| SCHEMBL1748844 | 0.73 | RAB9A (0.42) | MAPK1HTTMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636622-B1 | Isoxazole derivatives and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-23 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |