Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8974113 | 0.83 | PTGS2 (0.46) | PTGS2PTGS1CA12CA9CA1 | |
| SCHEMBL8974106 | 0.75 | PTGS2 (0.48) | PTGS2PTGS1KMT2AHPGD | |
| Benzenesulfonamide SCHEMBL9117378 | 0.75 | PTGS1 (0.46) | PTGS2PTGS1FFAR4GAAKMT2A | |
| SCHEMBL6723796 | 0.74 | PTGS2 (0.70) | PTGS2PTGS1CA12CA9CA1 | |
| SCHEMBL8659227 | 0.73 | ERAP1 (0.46) | ERAP1FFAR4GAAKMT2AHTR6 | |
| SCHEMBL8659727 | 0.72 | STAT3 (0.50) | PTGS2ERAP1GAAKMT2AACLY | |
| SCHEMBL9117719 | 0.72 | PTGS2 (0.56) | PTGS2PTGS1CA12CA9CA1 | |
| SCHEMBL8654615 | 0.70 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL8974584 | 0.69 | KIF11 (0.55) | PTGS2PTGS1CA12CA9CA1 | |
| SCHEMBL6725618 | 0.69 | PTGS2 (0.74) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030656-A1 | SUBSTITUTED CYCLOPENTADIENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1995-11-16 | — | — | WO | claimed |