Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 8/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817153 | 0.73 | DHODH (0.38) | WDR5IRAK4CRACR2APDK1PDK2 | |
| SCHEMBL9117434 | 0.72 | CCNE2 (0.31) | RIPK1 | |
| SCHEMBL5162176 | 0.70 | CRACR2A (0.37) | RIPK1CRACR2AGAAKDM4EPDK2 | |
| SCHEMBL7807338 | 0.69 | IRAK4 (0.35) | WDR5IRAK4ELANEGAA | |
| SCHEMBL9113721 | 0.68 | RXRA (0.37) | RIPK1 | |
| SCHEMBL9115252 | 0.68 | TRPV1 (0.47) | — | |
| SCHEMBL8890522 | 0.65 | PTGDR2 (0.38) | — | |
| SCHEMBL9239396 | 0.65 | KLKB1 (0.31) | IRAK4 | |
| SCHEMBL9239389 | 0.65 | KLKB1 (0.31) | IRAK4 | |
| SCHEMBL1194806 | 0.65 | DGAT1 (0.41) | GAAKDM4EMEN1CASP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025105-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD (GB) | 1995-09-21 | — | — | WO | claimed |
| WO-1995025105-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD (GB) | 1995-09-21 | — | — | WO | disclosed |