Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1194806 | 0.76 | DGAT1 (0.41) | KLKB1DGAT1LMNAPOLBGAA | |
| SCHEMBL17067013 | 0.75 | L3MBTL1 (0.40) | KLKB1DGAT1LMNAPOLBGAA | |
| SCHEMBL5212788 | 0.75 | LMNA (0.41) | KLKB1DGAT1LMNAPOLBGAA | |
| SCHEMBL9236693 | 0.74 | UCHL1 (0.33) | IRAK4KLKB1DGAT1WDR5GAA | |
| SCHEMBL9239389 | 0.73 | KLKB1 (0.31) | IRAK4KLKB1DGAT1RXFP1ALDH1A1 | |
| SCHEMBL9239396 | 0.73 | KLKB1 (0.31) | IRAK4KLKB1DGAT1RXFP1ALDH1A1 | |
| SCHEMBL7807872 | 0.72 | DGAT1 (0.31) | IRAK4DGAT1GAA | |
| SCHEMBL2089325 | 0.71 | KDM4E (0.50) | DGAT1GAAALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7817153 | 0.70 | DHODH (0.38) | IRAK4KLKB1WDR5 | |
| SCHEMBL8328384 | 0.69 | HDAC6 (0.45) | LMNAALDH1A1TDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156048-A1 | Heteroaroyl-isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 2001-11-21 | — | — | EP | disclosed |
| US-5480857-A | Herbicidal 4-heteroaroylisoxazole derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| WO-1995025099-A1 | 2-CYANO-1,3-DIONE DERIVATIVES USEFUL AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-09-21 | — | — | WO | disclosed |
| EP-0588357-A1 | Isoxazoles derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-03-23 | — | — | EP | disclosed |