Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.37 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 3/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27513121 | 0.75 | DHODH (0.46) | DHODHCRACR2APDE2AEPHX2 | |
| SCHEMBL7821033 | 0.74 | DHODH (0.38) | DHODHCRACR2APDE2AEPHX2 | |
| SCHEMBL9117428 | 0.73 | WDR5 (0.39) | CRACR2APDK1PDK2WDR5IRAK4 | |
| SCHEMBL18053852 | 0.72 | DHODH (0.50) | DHODHCRACR2A | |
| SCHEMBL1194806 | 0.72 | DGAT1 (0.41) | KLKB1 | |
| SCHEMBL17067013 | 0.70 | L3MBTL1 (0.40) | KLKB1PDK2 | |
| SCHEMBL5212788 | 0.70 | LMNA (0.41) | KLKB1 | |
| SCHEMBL7807338 | 0.70 | IRAK4 (0.35) | KLKB1WDR5IRAK4 | |
| SCHEMBL8488832 | 0.69 | DHODH (0.46) | DHODH | |
| SCHEMBL8607848 | 0.69 | DHODH (0.44) | DHODHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156048-A1 | Heteroaroyl-isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 2001-11-21 | — | — | EP | claimed |
| EP-0588357-A1 | Isoxazoles derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-03-23 | — | — | EP | claimed |
| EP-1156048-A1 | Heteroaroyl-isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 2001-11-21 | — | — | EP | disclosed |
| US-5480857-A | Herbicidal 4-heteroaroylisoxazole derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |
| EP-0588357-A1 | Isoxazoles derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-03-23 | — | — | EP | disclosed |