Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477638 | 0.85 | DAO (0.61) | DAOKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL7479392 | 0.83 | HTR7 (0.55) | KDM4EMAPTALDH1A1HPGDMGLL | |
| SCHEMBL194512 | 0.78 | DAO (0.69) | DAOKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL3975023 | 0.75 | MGLL (0.55) | KDM4EMAPTALDH1A1HPGDHTT | |
| SCHEMBL6981145 | 0.75 | HSD17B10 (0.74) | KDM4EMAPTALDH1A1HPGDHTT | |
| SCHEMBL9118924 | 0.74 | ALDH1A1 (0.50) | KDM4EMAPTALDH1A1HPGDHTT | |
| SCHEMBL12792523 | 0.74 | DAO (0.63) | DAOKDM4EMAPTALDH1A1HPGD | |
| SCHEMBL11689735 | 0.73 | HSD17B10 (0.48) | KDM4EMAPTALDH1A1HPGDHTT | |
| SCHEMBL28181208 | 0.73 | MGLL (0.47) | KDM4EMAPTALDH1A1HPGDHTT | |
| SCHEMBL3150761 | 0.71 | DAO (0.60) | DAOMAPTMGLLHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477819-B1 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1995-03-15 | — | — | EP | disclosed |
| US-5200422-A | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-04-06 | — | — | US | disclosed |
| EP-0477819-A2 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1992-04-01 | — | — | EP | disclosed |