Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183988 | 0.90 | MTNR1A (0.38) | MTNR1AMTNR1BKDM4ESMN1; SMN2LMNA | |
| SCHEMBL6182096 | 0.83 | AOC3 (0.39) | MTNR1AMTNR1BKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL6183171 | 0.82 | MTNR1A (0.40) | MTNR1AMTNR1BKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL9239223 | 0.79 | MTNR1A (0.38) | MTNR1AMTNR1BKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL9118552 | 0.77 | ACVRL1 (0.43) | MTNR1AMTNR1BKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL8489055 | 0.74 | NPC1 (0.34) | SMN1; SMN2KMT2ATSHR | |
| SCHEMBL9235242 | 0.74 | MAOB (0.32) | MTNR1AMTNR1BKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL6184434 | 0.73 | MAOB (0.34) | MTNR1AMTNR1BKDM4ESMN1; SMN2NPSR1 | |
| SCHEMBL6441958 | 0.71 | MEP1B (0.34) | MTNR1BALDH1A1TSHRHPGD | |
| SCHEMBL5779522 | 0.70 | PTGS2 (0.43) | AOC3MAOBMEN1KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160244-B1 | Isoxazole derivatives and their use as herbicides | BAYER AGRICULTURE LTD (GB) | 2005-10-19 | — | — | EP | disclosed |
| EP-1160244-A1 | Isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-12-05 | — | — | EP | disclosed |
| US-5489570-A | PRE- OR POST-EMERGENCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1996-02-06 | — | — | US | disclosed |
| EP-0636622-A1 | Isoxazole derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |