Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10772707 | 0.98 | CYP1A2 (0.44) | CYP1A2PDGFRBPDGFRAPDE10AKDM1A | |
| SCHEMBL11597016 | 0.91 | CYP1A2 (0.50) | CYP1A2PDGFRBPDGFRAPDE10AKDM1A | |
| SCHEMBL28151161 | 0.89 | CYP1A2 (0.48) | CYP1A2PDGFRBPDGFRAPDE10AKDM1A | |
| SCHEMBL3396692 | 0.85 | CYP1A2 (0.55) | CYP1A2PDGFRBPDGFRAPDE10AKDM1A | |
| SCHEMBL30195937 | 0.85 | MAOA (0.48) | CYP1A2PDGFRBPDGFRAPDE10AKDM1A | |
| SCHEMBL4817358 | 0.85 | CYP1A2 (0.44) | CYP1A2PDGFRBPDGFRAPDE10AKDM1A | |
| SCHEMBL859430 | 0.85 | TRPV1 (0.56) | CYP1A2PDE10ATRPV1 | |
| SCHEMBL9467100 | 0.85 | ALDH1A1 (0.46) | CYP1A2PDGFRBPDGFRAPDE10AKDM1A | |
| SCHEMBL8668667 | 0.85 | CYP1A2 (0.44) | CYP1A2PDGFRBPDGFRAPDE10AKDM1A | |
| SCHEMBL4865405 | 0.85 | MAOA (0.48) | CYP1A2PDGFRBPDGFRAPDE10AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069366-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | JANSSEN-CILAG (NJ) | 2010-03-18 | — | — | US | disclosed |
| US-5478938-A | Antagonists for angiotensin II receptors; hypotensive, cardiotonic agents; cognitive activators | ROUSSEL UCLAF (FR) | 1995-12-26 | — | — | US | disclosed |
| US-5324839-A | Hypotensive agents, gastrointestinal and urogenital disorders | ROUSSEL-UCLAF (FR) | 1994-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069366-A1 | ANTIBACTERIAL QUINOLINE DERIVATIVES | NQO2, NDUFB5, NDUFB7 | CYP1A2 198/4885PDGFRB 4002/4885PDGFRA 4266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.