SCHEMBL9119277

SCHEMBL9119277

CCC(C)Oc1ccc(OCc2ccc(C)cc2)c(Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 4/20 0.43
HPGD P15428 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PPARG P37231 1/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
RXRG P48443 1/20 0.41
PDK2 Q15119 1/20 0.41
HRH3 Q9Y5N1 2/20 0.40
MAOB P27338 1/20 0.40
P2RX3 P56373 6/20 0.39
PARP10 Q53GL7 1/20 0.39
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9119032 0.91 MRGPRX4 (0.49) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9117119 0.91 MRGPRX4 (0.43) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9292010 0.88 APP (0.46) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9292640 0.88 CCR5 (0.45) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9120222 0.88 PPARA (0.48) MRGPRX4HPGDPPARGMAOB
SCHEMBL9586004 0.85 MRGPRX4 (0.50) MRGPRX4PPARGRXRARXRBRXRG
SCHEMBL9586217 0.84 MRGPRX4 (0.47) MRGPRX4PDK2MAOB
SCHEMBL9292164 0.82 MRGPRX4 (0.51) MRGPRX4RXRARXRBRXRGMAOB
SCHEMBL9120596 0.81 RAB9A (0.48) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL13929749 0.78 MRGPRX4 (0.58) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5302619-A Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-04-12 US claimed
US-5262441-A APPLYING INSECTICIDE TO INSECT OR LOCUS WHERE INSECT PROPAGATES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-11-16 US claimed
EP-0504812-A2 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-09-23 EP claimed
JP-5178704-A None JP disclosed
EP-0504812-B1 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1995-09-06 EP disclosed
US-5302619-A Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-04-12 US disclosed
US-5262441-A APPLYING INSECTICIDE TO INSECT OR LOCUS WHERE INSECT PROPAGATES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-11-16 US disclosed
JP-H05178704-A AROMATIC COMPOUND, ITS PRODUCTION AND PEST-CONTROLLING DRUG CONTAINING THE SAME COMPOUND AS ACTIVE COMPONENT SUMITOMO CHEM CO LTD 1993-07-20 JP disclosed
EP-0504812-A2 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-09-23 EP disclosed