SCHEMBL9117119

SCHEMBL9117119

CCc1ccc(COc2ccc(OC(C)CC)cc2Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 5/20 0.43
HPGD P15428 3/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
RXRA P19793 2/20 0.41
RXRB P28702 2/20 0.41
RXRG P48443 1/20 0.41
PDK2 Q15119 1/20 0.41
HRH3 Q9Y5N1 1/20 0.39
ACACB O00763 2/20 0.38
CSNK2A1 P68400 1/20 0.38
ATM Q13315 1/20 0.38
PPARD Q03181 2/20 0.38
PPARA Q07869 2/20 0.38
USP2 O75604 1/20 0.38
ENPP2 Q13822 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9119032 0.92 MRGPRX4 (0.49) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9119277 0.91 MRGPRX4 (0.43) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9120222 0.90 PPARA (0.48) MRGPRX4HPGDPPARDPPARA
SCHEMBL9292640 0.90 CCR5 (0.45) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9292010 0.90 APP (0.46) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9586004 0.86 MRGPRX4 (0.50) MRGPRX4RXRARXRBRXRGPPARD
SCHEMBL9586217 0.85 MRGPRX4 (0.47) MRGPRX4PDK2ATMPPARDPPARA
SCHEMBL9292164 0.83 MRGPRX4 (0.51) MRGPRX4RXRARXRBRXRGENPP2
SCHEMBL9120596 0.82 RAB9A (0.48) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL8959153 0.78 GLA (0.48) HPGDSMN1; SMN2CSNK2A1PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0504812-B1 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1995-09-06 EP claimed
US-5302619-A Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-04-12 US claimed
US-5262441-A APPLYING INSECTICIDE TO INSECT OR LOCUS WHERE INSECT PROPAGATES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-11-16 US claimed
EP-0504812-A2 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-09-23 EP claimed
EP-0504812-B1 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1995-09-06 EP disclosed
US-5302619-A Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-04-12 US disclosed
US-5262441-A APPLYING INSECTICIDE TO INSECT OR LOCUS WHERE INSECT PROPAGATES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-11-16 US disclosed
EP-0504812-A2 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-09-23 EP disclosed