SCHEMBL9292010

SCHEMBL9292010

CCC(C)Oc1ccc(OCc2ccc(I)cc2)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
APP P05067 13/20 0.46
MRGPRX4 Q96LA9 2/20 0.41
HPGD P15428 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
RXRA P19793 2/20 0.40
RXRB P28702 2/20 0.40
RXRG P48443 1/20 0.40
PDK2 Q15119 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9117119 0.90 MRGPRX4 (0.43) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9119032 0.90 MRGPRX4 (0.49) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9119277 0.88 MRGPRX4 (0.43) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9120222 0.87 PPARA (0.48) MRGPRX4HPGD
SCHEMBL9292640 0.87 CCR5 (0.45) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9586004 0.84 MRGPRX4 (0.50) MRGPRX4RXRARXRBRXRG
SCHEMBL9586217 0.82 MRGPRX4 (0.47) MRGPRX4PDK2
SCHEMBL9292164 0.81 MRGPRX4 (0.51) MRGPRX4RXRARXRBRXRG
SCHEMBL9120596 0.80 RAB9A (0.48) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL8959153 0.76 GLA (0.48) HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5302619-A Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-04-12 US claimed
US-5262441-A APPLYING INSECTICIDE TO INSECT OR LOCUS WHERE INSECT PROPAGATES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-11-16 US claimed
EP-0504812-A2 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-09-23 EP claimed