Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120292 | 0.80 | MEN1 (0.65) | MEN1KMT2AL3MBTL1POLBNPC1 | |
| SCHEMBL8619524 | 0.80 | L3MBTL1 (0.69) | MEN1KMT2AL3MBTL1POLBGAA | |
| SCHEMBL11218130 | 0.79 | MAPT (0.69) | MEN1KMT2AL3MBTL1POLBNPC1 | |
| SCHEMBL9116525 | 0.78 | MAPT (0.62) | MEN1KMT2AL3MBTL1NPC1GAA | |
| SCHEMBL9119303 | 0.78 | MEN1 (0.56) | MEN1KMT2AL3MBTL1POLBNPC1 | |
| SCHEMBL16148164 | 0.78 | RORC (0.60) | MEN1KMT2AL3MBTL1POLBNPC1 | |
| SCHEMBL7015582 | 0.76 | L3MBTL1 (0.39) | MEN1KMT2AL3MBTL1POLBNPC1 | |
| SCHEMBL27908762 | 0.75 | GPR35 (0.64) | MEN1KMT2AL3MBTL1POLBNPC1 | |
| SCHEMBL9118458 | 0.74 | KCNMA1 (0.66) | MEN1KMT2AL3MBTL1POLBNPC1 | |
| SCHEMBL2043906 | 0.74 | MEN1 (0.58) | MEN1KMT2AL3MBTL1POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477819-B1 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1995-03-15 | — | — | EP | disclosed |
| US-5200422-A | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-04-06 | — | — | US | disclosed |
| EP-0477819-A2 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1992-04-01 | — | — | EP | disclosed |