Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9121605 | 0.84 | CCR1 (0.55) | RXFP1CCR1CCR2KDM4EHPGD | |
| SCHEMBL9284831 | 0.83 | CCR2 (0.57) | RXFP1CCR1CCR2LMNAKDM4E | |
| SCHEMBL9118404 | 0.81 | RXFP1 (0.53) | RXFP1CCR1CCR2LMNAHTT | |
| SCHEMBL9122911 | 0.80 | CCR1 (0.48) | RXFP1CCR1CCR2LMNAHTT | |
| SCHEMBL16302025 | 0.80 | SCN8A (0.53) | TAS2R14MAPTMRGPRX4TDP1CFTR | |
| SCHEMBL30691780 | 0.80 | HDAC1 (0.55) | LMNAHTTHDAC1HDAC8HDAC6 | |
| SCHEMBL6808607 | 0.79 | CCR1 (0.43) | RXFP1CCR1CCR2LMNAHTT | |
| SCHEMBL1365182 | 0.78 | CFTR (0.64) | RXFP1CCR1CCR2LMNAKDM4E | |
| SCHEMBL9118380 | 0.77 | GRIK1 (0.47) | RXFP1CCR1CCR2LMNAHTT | |
| SCHEMBL6808609 | 0.77 | TAS2R14 (0.48) | CCR1CCR2HTTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033715-A1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |