Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808607 | 0.85 | CCR1 (0.43) | TAS2R14CCR1CCR2KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL6141535 | 0.80 | CCR2 (0.53) | TAS2R14CCR1CCR2MRGPRX4AKR1B1 | |
| SCHEMBL16302025 | 0.77 | SCN8A (0.53) | TAS2R14MRGPRX4CFTRMAPTTDP1 | |
| SCHEMBL9119563 | 0.77 | RXFP1 (0.49) | TAS2R14CCR1CCR2KDM4EHPGD | |
| SCHEMBL6141415 | 0.75 | TAS2R14 (0.67) | TAS2R14CCR1CCR2AKR1B1AKR1C4 | |
| SCHEMBL9122911 | 0.73 | CCR1 (0.48) | TAS2R14CCR1CCR2KDM4EHPGD | |
| SCHEMBL6141345 | 0.73 | TAS2R14 (0.49) | TAS2R14KDM4EHPGDMRGPRX4AKR1B1 | |
| SCHEMBL6802907 | 0.73 | TAS2R14 (0.49) | TAS2R14KDM4EHPGDMRGPRX4AKR1B1 | |
| SCHEMBL1365182 | 0.73 | CFTR (0.64) | CCR1CCR2KDM4EHPGDMRGPRX4 | |
| SCHEMBL9118404 | 0.71 | RXFP1 (0.53) | TAS2R14CCR1CCR2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142993-A1 | Inhibitors of HCV NS5B polymerase | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142993-A1 | Inhibitors of HCV NS5B polymerase | POLRMT, POLR1E, CTDSP1 | TAS2R14 4336/4885CCR1 1494/4885CCR2 2656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.