Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTR1D | P28221 | 2/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436334 | 0.75 | SMN1; SMN2 (0.63) | SMN1; SMN2POLBGAAKDM4EALDH1A1 | |
| SCHEMBL8126457 | 0.74 | MTNR1A (0.53) | SMN1; SMN2POLBKDM4EALDH1A1MAPT | |
| SCHEMBL9119618 | 0.74 | SMN1; SMN2 (0.55) | SMN1; SMN2POLBGAAKDM4EALDH1A1 | |
| SCHEMBL20562108 | 0.74 | CA2 (0.54) | SMN1; SMN2HTR6KDM4EALDH1A1HPGD | |
| SCHEMBL9295805 | 0.73 | MTNR1A (0.67) | ALDH1A1 | |
| SCHEMBL18045173 | 0.72 | ALDH1A1 (0.77) | SMN1; SMN2POLBGAAKDM4EALDH1A1 | |
| SCHEMBL9253882 | 0.71 | ALDH1A1 (0.51) | SMN1; SMN2HTR1DHTR6POLBGAA | |
| SCHEMBL29699265 | 0.71 | KDM4E (0.60) | SMN1; SMN2POLBGAAKDM4EALDH1A1 | |
| SCHEMBL18766190 | 0.71 | KDM4E (0.60) | SMN1; SMN2POLBGAAKDM4EALDH1A1 | |
| SCHEMBL9122419 | 0.71 | MTNR1A (0.61) | HTR1DHTR6ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380750-A | Arylethylamine compounds | ADIR ET COMPAGNIE (FR) | 1995-01-10 | — | — | US | disclosed |
| US-5308866-A | Treatment of melatonin related disorders, sleep disorders, psychological disorders | ADIR ET COMPAGNIE (FR) | 1994-05-03 | — | — | US | disclosed |
| US-5276051-A | Treatment of melatoninergic system, antiischemic agents and skin disorders using aminoalkylindole compounds | ADIR ET COMPAGNIE (FR) | 1994-01-04 | — | — | US | disclosed |