Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9157732 | 0.99 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL9253748 | 0.89 | KDM4E (0.48) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL9156668 | 0.88 | KDM4E (0.47) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL9159270 | 0.80 | MTNR1A (0.65) | MTNR1AMTNR1BHTR2C | |
| SCHEMBL9244953 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL18397738 | 0.71 | PPARG (0.65) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL9119624 | 0.71 | SMN1; SMN2 (0.54) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL18397733 | 0.70 | LOXL2 (0.66) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL9253876 | 0.70 | MAPT (0.51) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL9162577 | 0.70 | MTNR1A (0.56) | SMN1; SMN2MTNR1AMTNR1BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5386034-A | Treatment of sleeping, psychological and nervous system disorders; anxiolytic agents, ovulation regulators | ADIR ET COMPAGNIE (FR) | 1995-01-31 | — | — | US | disclosed |
| US-5322849-A | Treating sleep disorders | ADIR ET COMPAGNIE (FR) | 1994-06-21 | — | — | US | disclosed |
| US-5300507-A | Treating sleep disorders | ADIR ET COMPAGNIE (FR) | 1994-04-05 | — | — | US | disclosed |
| US-5240919-A | Treating sleep disorders | ADIR ET COMPAGNIE (FR) | 1993-08-31 | — | — | US | disclosed |