Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120254 | 1.00 | CTRB1 (0.41) | CTRB1LMNAMCL1ALDH1A1MAPT | |
| SCHEMBL9119658 | 0.91 | CTRB1 (0.40) | CTRB1LMNAMCL1ALDH1A1MAPT | |
| SCHEMBL9119879 | 0.91 | CTRB1 (0.40) | CTRB1LMNAMCL1ALDH1A1MAPT | |
| SCHEMBL9241436 | 0.91 | CTRB1 (0.40) | CTRB1LMNAMCL1ALDH1A1MAPT | |
| SCHEMBL21866174 | 0.89 | KMT2A (0.40) | CTRB1MCL1ALDH1A1MAPTHPGD | |
| SCHEMBL9208262 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDTDP1POLB | |
| SCHEMBL9727854 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MAPTHPGDTDP1POLB | |
| SCHEMBL9118887 | 0.84 | KMT2A (0.39) | LMNAALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9118882 | 0.84 | KMT2A (0.39) | LMNAALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL10362668 | 0.81 | MMP2 (0.49) | ALDH1A1MAPTHPGDTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463046-A | 1-β-methyl-2-thiolic carbapenem derivatives | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 1995-10-31 | — | — | US | disclosed |