Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5250855 | 0.74 | ALDH1A1 (0.44) | GPR35TDP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL1774516 | 0.73 | — | — | |
| SCHEMBL14267778 | 0.70 | GPR35 (0.40) | GPR35TDP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL20568749 | 0.69 | MAPT (0.40) | GPR35TDP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL14672458 | 0.69 | TDP1 (0.59) | GPR35TDP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL3975806 | 0.68 | KDM4E (0.39) | GPR35TDP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL1516544 | 0.68 | TSHR (0.47) | GPR35TDP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL31661340 | 0.68 | KDM4E (0.43) | GPR35TDP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL9483533 | 0.68 | ALDH1A1 (0.46) | TDP1TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL28391943 | 0.67 | TDP1 (0.81) | GPR35TDP1TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57067557-A | — | — | None | — | — | JP | disclosed |
| JP-58124765-A | — | — | None | — | — | JP | disclosed |
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |
| EP-0372263-B1 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID CO (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5204332-A | PYRROLE CARBONITRILE AND NITROPYRROLE INSECTICIDAL AND ACARICIDAL AND MOLLUSCICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1993-04-20 | — | — | US | disclosed |
| US-5162308-A | Pyrrole carbonitrile and nitropyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0372263-A2 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |
| EP-0080051-B1 | HETEROCYCLIC COMPOUNDS AND ANTIBACTERIAL AND ANTIFUNGAL COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENTS | MEIJI SEIKA KAISHA LTD. (JP) | 1986-02-05 | — | — | EP | disclosed |
| US-4563472-A | BACTERICIDES, FUNGICIDES | MEIJI SEIKA KAISHA, LTD. (JP) | 1986-01-07 | — | — | US | disclosed |
| JP-S58124765-A | PYRROLE DERIVATIVE, ITS PREPARATION, AND ANTIFUNGAL CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD | 1983-07-25 | — | — | JP | disclosed |
| EP-0080051-A2 | Heterocyclic compounds and antibacterial and antifungal compositions containing the same as active ingredients | MEIJI SEIKA KAISHA LTD. (JP) | 1983-06-01 | — | — | EP | disclosed |
| JP-S5767557-A | PRODUCTION OF SF-2080A SUBSTANCE AND ANTIMYCOTIC CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD | 1982-04-24 | — | — | JP | disclosed |