Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1516544 | 0.72 | TSHR (0.47) | KDM4EGPR35CA12CA9TSHR | |
| SCHEMBL9124172 | 0.68 | GPR35 (0.45) | KDM4EGPR35TSHRCYP3A4HPGD | |
| SCHEMBL458846 | 0.68 | KDM4E (0.61) | KDM4EGPR35CA12CA9TSHR | |
| SCHEMBL3975806 | 0.68 | KDM4E (0.39) | KDM4EGPR35TSHRCYP3A4HPGD | |
| SCHEMBL29783588 | 0.68 | TSHR (0.56) | GPR35TSHRCYP3A4HPGDMAPK1 | |
| SCHEMBL3240210 | 0.68 | TSHR (0.56) | GPR35TSHRCYP3A4HPGDMAPK1 | |
| SCHEMBL16070109 | 0.67 | KDM4E (0.39) | KDM4EGPR35CA12CA9TSHR | |
| SCHEMBL4708063 | 0.67 | KDM4E (0.38) | KDM4EGPR35TSHRCYP3A4HPGD | |
| SCHEMBL4708066 | 0.67 | KDM4E (0.38) | KDM4EGPR35TSHRCYP3A4HPGD | |
| SCHEMBL5250855 | 0.65 | ALDH1A1 (0.44) | KDM4EGPR35TSHRCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151517-A1 | THIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS ASSOCIATED WITH MISSFOLDING OF ALPHA-SYNUCLEIN PROTEIN | WAVEBREAK THERAPEUTICS LIMITED (US) | 2025-07-17 | — | — | WO | disclosed |