Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12767969 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL9122816 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL9123423 | 0.79 | TSHR (0.47) | ALDH1A1HTTSMN1; SMN2POLBHPGD | |
| SCHEMBL9124731 | 0.76 | HTR1B (0.50) | ALDH1A1KDM4EL3MBTL1LMNAMAPT | |
| SCHEMBL10753281 | 0.75 | ALDH1A1 (0.47) | ALDH1A1HTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL9663296 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL9123701 | 0.74 | KMT2A (0.41) | ALDH1A1HPGDMAPK1KMT2A | |
| SCHEMBL772528 | 0.73 | ALOX15 (0.55) | ALDH1A1HTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL10749843 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HTTKDM4ESMN1; SMN2POLB | |
| SCHEMBL12586735 | 0.72 | ALDH1A1 (0.45) | ALDH1A1HTTKDM4ESMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492615-B1 | Process for producing biguanide derivative | IDEMITSU KOSAN CO (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5286905-A | Heating hydrogen halide salt of phenoxyalkylamine with dicyandiamide in paraffinic hydrocarbon solvent | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1994-02-15 | — | — | US | disclosed |
| EP-0492615-A1 | Process for producing biguanide derivative | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-07-01 | — | — | EP | disclosed |