Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125507 | 1.00 | ALDH1A1 (0.47) | ALDH1A1PKMNPC1SMN1; SMN2BCL2A1 | |
| SCHEMBL9125451 | 0.83 | MAPT (0.41) | MAPT | |
| SCHEMBL9125443 | 0.83 | MAPT (0.41) | MAPT | |
| SCHEMBL9674128 | 0.74 | SLC6A2 (0.49) | ALDH1A1NPC1SMN1; SMN2BCL2A1MAPT | |
| SCHEMBL9736113 | 0.74 | SLC6A2 (0.49) | ALDH1A1NPC1SMN1; SMN2BCL2A1MAPT | |
| SCHEMBL2547161 | 0.73 | ALDH1A1 (0.60) | ALDH1A1PKMNPC1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL9123748 | 0.73 | MEN1 (0.50) | ALDH1A1PKMNPC1SMN1; SMN2BCL2A1 | |
| Hydrochloric Acid SCHEMBL9123750 | 0.73 | MEN1 (0.50) | ALDH1A1PKMNPC1SMN1; SMN2BCL2A1 | |
| SCHEMBL2550526 | 0.72 | ALDH1A1 (0.58) | ALDH1A1PKMNPC1SMN1; SMN2LMNA | |
| SCHEMBL2579539 | 0.71 | LMNA (0.72) | ALDH1A1SMN1; SMN2MAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395934-A | Antiarrhythmia agents and cardiovascular disorders | EGIS GYOGYSZERGYAR (HU) | 1995-03-07 | — | — | US | disclosed |