Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 12/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523527 | 0.89 | MEN1 (0.36) | MEN1CYP2D6CYP2C19KMT2ATACR1 | |
| Hydrochloric Acid SCHEMBL9522102 | 0.83 | POLB (0.41) | MEN1KMT2AEPHX2TACR1SMN1; SMN2 | |
| SCHEMBL3361304 | 0.75 | KDM1A (0.56) | TACR1CACNA1FCHRM5CACNA1DCACNA1S | |
| SCHEMBL3360370 | 0.75 | MEN1 (0.58) | MEN1CYP2D6CYP2C19KMT2AEPHX2 | |
| SCHEMBL10370086 | 0.68 | TRPV6 (0.46) | MEN1KMT2AEPHX2SMN1; SMN2 | |
| SCHEMBL3360273 | 0.68 | ALDH1A1 (0.59) | MEN1KMT2ATACR1SMN1; SMN2KDM1A | |
| SCHEMBL3362808 | 0.68 | KDM1A (0.53) | MEN1KMT2AEPHX2SMN1; SMN2HSD11B1 | |
| SCHEMBL3361522 | 0.68 | KDM1A (0.53) | EPHX2TACR1SMN1; SMN2KDM1A | |
| SCHEMBL9126112 | 0.68 | KDM4E (0.40) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9123842 | 0.68 | KDM4E (0.40) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5413997-A | For treatment of osteoporosis | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-05-09 | — | — | US | disclosed |
| EP-0395093-A1 | Triphenylmethane derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |