Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 14/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126004 | 0.89 | MEN1 (0.46) | MEN1CYP2D6CYP2C19KMT2ATACR1 | |
| SCHEMBL10370086 | 0.80 | TRPV6 (0.46) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9126112 | 0.80 | KDM4E (0.40) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9123842 | 0.80 | KDM4E (0.40) | MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9522102 | 0.79 | POLB (0.41) | MEN1KMT2ATACR1SMN1; SMN2 | |
| SCHEMBL9126148 | 0.78 | KMT2A (0.46) | MEN1CYP2C19KMT2AMAOAMAOB | |
| SCHEMBL9520874 | 0.75 | KMT2A (0.50) | MEN1KMT2A | |
| SCHEMBL9124466 | 0.74 | KMT2A (0.54) | MEN1CYP2C19KMT2A | |
| SCHEMBL9125178 | 0.73 | NPC1 (0.37) | MEN1CYP2D6KMT2A | |
| SCHEMBL9125185 | 0.70 | MEN1 (0.38) | MEN1CYP2D6CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395093-B1 | TRIPHENYLMETHANE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5112867-A | Osteoporosis Treatment | KYOWA HAKKO GOGYO CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |