Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | DRD3 | P35462 | 5/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130345 | 0.81 | ALDH1A1 (0.40) | KMT2AALDH1A1L3MBTL1BCHESMN1; SMN2 | |
| SCHEMBL1963069 | 0.80 | — | — | |
| SCHEMBL9125633 | 0.80 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1BCHESMN1; SMN2MAPK1 | |
| SCHEMBL9127102 | 0.80 | ALDH1A1 (0.39) | KMT2AALDH1A1L3MBTL1BCHESMN1; SMN2 | |
| SCHEMBL9019581 | 0.80 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1BCHESMN1; SMN2LMNA | |
| SCHEMBL9795195 | 0.80 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1BCHESMN1; SMN2MAPK1 | |
| SCHEMBL9497980 | 0.78 | SMYD3 (0.44) | ALDH1A1L3MBTL1 | |
| SCHEMBL9497857 | 0.78 | SMYD3 (0.44) | ALDH1A1L3MBTL1 | |
| SCHEMBL9795527 | 0.78 | SMYD3 (0.44) | ALDH1A1L3MBTL1 | |
| SCHEMBL9127645 | 0.77 | MAPT (0.38) | POLBALDH1A1L3MBTL1BCHESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | disclosed |