Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A11 | Q9UPY5 | 2/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cysteine SCHEMBL14956977 | 1.00 | SLC7A11 (0.61) | SLC7A11PTGS1CRBNGRM5GRM1 | |
| Cysteine SCHEMBL3447686 | 0.84 | SLC7A11 (0.67) | SLC7A11PTGS1GRM5GRM1KDM4E | |
| Aspartic Acid SCHEMBL3460058 | 0.81 | GRIK1 (0.44) | SLC7A11CRBNGRM5GRM1KDM4E | |
| Aspartic Acid SCHEMBL3460059 | 0.81 | GRIK1 (0.44) | SLC7A11CRBNGRM5GRM1KDM4E | |
| Asparagine SCHEMBL27137678 | 0.79 | GRIK1 (0.43) | SLC7A11CRBNGRM5GRM1KDM4E | |
| Cysteine SCHEMBL4289403 | 0.78 | — | — | |
| Cysteine SCHEMBL7898895 | 0.78 | PTGS1 (1.00) | SLC7A11PTGS1GRM5GRM1ALDH1A1 | |
| Cysteine SCHEMBL339562 | 0.78 | PTGS1 (1.00) | SLC7A11PTGS1GRM5GRM1ALDH1A1 | |
| Cysteine SCHEMBL21110883 | 0.78 | PTGS1 (1.00) | SLC7A11PTGS1GRM5GRM1ALDH1A1 | |
| Cysteine SCHEMBL95110 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399411-A1 | SPECIFIC ANTIBODY-DRUG-CONJUGATES (ADCS) WITH KSP INHIBITORS AND ANTI-CD123-ANTIBODIES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2023-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399411-A1 | SPECIFIC ANTIBODY-DRUG-CONJUGATES (ADCS) WITH KSP INHIBITORS AND ANTI-CD123-ANTIBODIES | KIF23, SDCBP, KLK13 | SLC7A11 1594/4885PTGS1 3559/4885CRBN 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.