Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.68 |
| ▸ | SHBG | P04278 | 5/20 | 0.68 |
| ▸ | PGR | P06401 | 4/20 | 0.68 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.68 |
| ▸ | ESR1 | P03372 | 3/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.68 |
| ▸ | AR | P10275 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240496 | 1.00 | LMNA (0.68) | LMNASHBGPGRNR3C1TSHR | |
| SCHEMBL10444758 | 0.86 | NR3C1 (0.50) | LMNASHBGPGRNR3C1TSHR | |
| SCHEMBL15079251 | 0.86 | NR3C1 (0.50) | LMNASHBGPGRNR3C1TSHR | |
| SCHEMBL9128571 | 0.85 | SHBG (0.65) | LMNASHBGPGRNR3C1TSHR | |
| SCHEMBL9128581 | 0.85 | SHBG (0.65) | LMNASHBGPGRNR3C1TSHR | |
| SCHEMBL10605027 | 0.84 | LMNA (0.48) | LMNASHBGPGRNR3C1TSHR | |
| SCHEMBL11236389 | 0.82 | CYP3A4 (0.59) | LMNASHBGPGRNR3C1TSHR | |
| SCHEMBL11236392 | 0.82 | CYP3A4 (0.59) | LMNASHBGPGRNR3C1TSHR | |
| SCHEMBL13965592 | 0.81 | LMNA (0.67) | LMNASHBGPGRNR3C1TSHR | |
| SCHEMBL572198 | 0.81 | LMNA (0.67) | LMNASHBGPGRNR3C1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322349-A | Process for preparing 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |