Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.43 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9226597 | 0.86 | CES2 (0.54) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL27243952 | 0.82 | CES2 (0.49) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL8301590 | 0.81 | KCNQ3 (0.42) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL8875867 | 0.81 | KCNQ3 (0.43) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL28476035 | 0.81 | KCNQ3 (0.44) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL29037468 | 0.80 | KCNQ3 (0.42) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL4714984 | 0.79 | KCNQ3 (0.38) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL479072 | 0.77 | TSHR (0.65) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL27265284 | 0.77 | S1PR1 (0.45) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL9860507 | 0.77 | KCNQ3 (0.41) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385906-A | Treating gramnegative and grampositive bacterial infections | THE UPJOHN COMPANY (US) | 1995-01-31 | — | — | US | disclosed |