Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.43 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.42 |
| ▸ | CHRNG | P07510 | 2/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | CHRND | Q07001 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29037468 | 0.98 | KCNQ3 (0.42) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL9219903 | 0.88 | CHRNA1 (0.55) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL4714984 | 0.85 | KCNQ3 (0.38) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL10778548 | 0.84 | KCNQ3 (0.42) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL9128573 | 0.81 | KCNQ3 (0.43) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL1533349 | 0.79 | RAB9A (0.44) | MEN1MAPTCASP3KMT2ASENP7 | |
| SCHEMBL9431238 | 0.77 | MEN1 (0.49) | MEN1MAPTKMT2ALMNAHTT | |
| SCHEMBL29825107 | 0.77 | ALDH1A1 (0.58) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL15968586 | 0.77 | ALDH1A1 (0.58) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL27243952 | 0.77 | CES2 (0.49) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105792-B | Preparation method of ciprofloxacin key intermediate | 山东国邦药业有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-114105792-A | Preparation method of ciprofloxacin key intermediate | 山东国邦药业有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-114105792-B | Preparation method of ciprofloxacin key intermediate | 山东国邦药业有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-114105792-A | Preparation method of ciprofloxacin key intermediate | 山东国邦药业有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-107151242-B | 2-azolothiochromone compound, synthesis method thereof and application thereof in preparation of antifungal drugs | 南京工业大学 | 2020-05-22 | — | — | CN | disclosed |
| US-20150239864-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | SOOCHOW UNIVERSITY (CN) | 2015-08-27 | — | — | US | disclosed |
| EP-2889294-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | Soochow University (CN) | 2015-07-01 | — | — | EP | disclosed |
| CN-1298875-A | Process for preparing dinorfloxacin | CHAOYAO INST OF FINE CHEMICAL (CN) | 2001-06-13 | — | — | CN | disclosed |
| US-5672708-A | Process for the preparation of N-arylaminoacrylic acid derivatives and the use of N-arylaminoacrylic acid derivatives thus prepared for the preparation of 4-quinolone-3-carboxylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-30 | — | — | US | disclosed |
| US-4611080-A | Preparation of halogenated aroylacetic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239864-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | TXN2, TXN, TXNRD2 | KCNQ3 2417/4885KCNQ2 2937/4885KCNE1 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.