Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.42 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.41 |
| ▸ | CHRNG | P07510 | 2/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | CHRND | Q07001 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875867 | 0.98 | KCNQ3 (0.43) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL9219903 | 0.86 | CHRNA1 (0.55) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL4714984 | 0.84 | KCNQ3 (0.38) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL10778548 | 0.82 | KCNQ3 (0.42) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL9128573 | 0.80 | KCNQ3 (0.43) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL1533349 | 0.78 | RAB9A (0.44) | MEN1MAPTCASP3KMT2ASENP7 | |
| SCHEMBL29825107 | 0.76 | ALDH1A1 (0.58) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL9431238 | 0.76 | MEN1 (0.49) | MEN1MAPTKMT2ALMNAHTT | |
| SCHEMBL15968586 | 0.76 | ALDH1A1 (0.58) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL27243952 | 0.76 | CES2 (0.49) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114933543-B | Synthetic method of 3-cyclopropylamino-2- (2,4-dichloro-5-fluorobenzoyl) methyl acrylate | 山东国邦药业有限公司 | 2022-10-28 | — | — | CN | claimed |