Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | ESR1 | P03372 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TACR2 | P21452 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22701392 | 0.85 | L3MBTL1 (0.51) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL24081206 | 0.83 | NFKB1 (0.54) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL10462727 | 0.83 | MCHR1 (0.51) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| Propane SCHEMBL27619750 | 0.82 | ESR1 (0.79) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL21632769 | 0.82 | ESR1 (0.79) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL9159934 | 0.81 | L3MBTL1 (0.59) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10463066 | 0.81 | CASP3 (0.59) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL20411973 | 0.81 | NFKB1 (0.53) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL20233 | 0.80 | ESR1 (0.83) | NPC1RAB9ASMN1; SMN2MAPTSTAT3 | |
| SCHEMBL10462296 | 0.80 | MCHR1 (0.49) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399575-A | Antiallergens | BOEHRINGER MANNHEIM GMBH (DE) | 1995-03-21 | — | — | US | disclosed |