Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 15/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 11/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9485070 | 0.87 | HTT (0.56) | TBXAS1TBXA2RMEN1KMT2A | |
| SCHEMBL9130373 | 0.84 | TBXAS1 (0.59) | TBXAS1TBXA2RNAMPTMEN1KMT2A | |
| SCHEMBL9485978 | 0.81 | KMT2A (0.52) | TBXAS1TBXA2RMEN1KMT2A | |
| SCHEMBL9484732 | 0.79 | F2 (0.57) | TBXAS1TBXA2R | |
| SCHEMBL10836333 | 0.79 | TBXAS1 (0.71) | TBXAS1TBXA2R | |
| SCHEMBL9484173 | 0.77 | MEN1 (0.60) | TBXA2RMEN1KMT2APOLB | |
| SCHEMBL9129291 | 0.77 | F2 (0.64) | TBXAS1TBXA2RADRB2ADRB1ADRB3 | |
| SCHEMBL10462759 | 0.75 | MEN1 (0.64) | TBXA2RMEN1KMT2A | |
| SCHEMBL9207918 | 0.74 | TBXAS1 (0.73) | TBXAS1TBXA2R | |
| SCHEMBL9754552 | 0.74 | MEN1 (0.84) | TBXA2RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564499-A1 | NOVEL AMINES, PROCESS FOR PRODUCING THEM AND MEDICAMENTS CONTAINING SAID COMPOUNDS. | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-13 | — | — | EP | disclosed |