Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EEF2K | O00418 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CTRC | Q99895 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129357 | 1.00 | SIRT1 (0.57) | SIRT1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9565691 | 0.89 | MEN1 (0.48) | SIRT1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9565692 | 0.89 | MEN1 (0.48) | SIRT1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9565687 | 0.84 | SIRT1 (0.54) | SIRT1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9565688 | 0.84 | SIRT1 (0.54) | SIRT1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9565698 | 0.81 | EEF2K (0.52) | SIRT1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9565707 | 0.81 | MAPT (0.68) | SIRT1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9565701 | 0.81 | MAPT (0.68) | SIRT1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8539935 | 0.81 | MAPT (0.57) | SIRT1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9565708 | 0.81 | MAPT (0.68) | SIRT1ALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7053380-A | — | — | None | — | — | JP | disclosed |
| JP-5213755-A | — | — | None | — | — | JP | disclosed |
| JP-H0753380-A | THERAPEUTIC AGENT FOR HYPERLIPEMIA AND HYPERURICEMIA | JAPAN ENERGY CORP | 1995-02-28 | — | — | JP | disclosed |
| JP-H05213755-A | THERAPEUTIC AGENT FOR HEPATOPATHY | NIKKO KYODO CO LTD | 1993-08-24 | — | — | JP | disclosed |
| EP-0546661-A1 | Pyrimidine derivatives, method for preparation thereof and pharmaceutical composition having said derivatives as active elements | JAPAN ENERGY CORPORATION (JP) | 1993-06-16 | — | — | EP | disclosed |