Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15635118 | 0.87 | ALDH1A1 (0.52) | ALDH1A1LMNATSHRCOMTMAPT | |
| SCHEMBL25380051 | 0.85 | LMNA (0.65) | ALDH1A1LMNATSHRMAPTMAPK1 | |
| SCHEMBL7650970 | 0.83 | LMNA (0.55) | ALDH1A1LMNATSHRMAPTMAPK1 | |
| SCHEMBL3834688 | 0.83 | LMNA (0.61) | ALDH1A1LMNATSHRMAPTMAPK1 | |
| SCHEMBL26669062 | 0.83 | MEN1 (0.35) | ALDH1A1LMNAALOX15 | |
| SCHEMBL3835751 | 0.81 | LMNA (0.64) | ALDH1A1LMNATSHRMAPTMAPK1 | |
| SCHEMBL13077107 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNATSHRCOMTMAPT | |
| SCHEMBL22299925 | 0.79 | TSHR (0.38) | ALDH1A1TSHRTP53 | |
| SCHEMBL23407291 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNATSHRCOMTMAPT | |
| SCHEMBL8847407 | 0.78 | ALDH1A1 (0.43) | ALDH1A1LMNACOMTMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220056033-A1 | ADENOSINE RECEPTOR ANTAGONISTS AND USES THEREOF | TEON THERAPEUTICS, INC. | 2022-02-24 | — | — | US | disclosed |
| US-11124515-B2 | Adenosine receptor antagonists and uses thereof | TEON THERAPEUTICS, INC. (US) | 2021-09-21 | — | — | US | disclosed |
| US-20210163483-A1 | ADENOSINE RECEPTOR ANTAGONISTS AND USES THEREOF | TEON THERAPEUTICS, INC. | 2021-06-03 | — | — | US | disclosed |
| WO-2019173380-A1 | ADENOSINE RECEPTOR ANTAGONISTS AND USES THEREOF | TEON THERAPEUTICS, INC. (US) | 2019-09-12 | — | — | WO | disclosed |
| US-5401868-A | Sulfiding and esterification to form chemical intermediates | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUCTIONSAKTIESELSKAB) (DK) | 1995-03-28 | — | — | US | disclosed |
| EP-0541550-B1 | NEW INTERMEDIATES, THEIR PRODUCTION AND USE | LEO PHARM PROD LTD (DK) | 1994-09-07 | — | — | EP | disclosed |
| EP-0541550-A1 | NEW INTERMEDIATES, THEIR PRODUCTION AND USE. | LEO PHARM PROD LTD (DK) | 1993-05-19 | — | — | EP | disclosed |
| WO-1991010639-A1 | NEW INTERMEDIATES, THEIR PRODUCTION AND USE | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1991-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163483-A1 | ADENOSINE RECEPTOR ANTAGONISTS AND USES THEREOF | ADORA2A, ADORA2B, ADORA3 | ALDH1A1 817/4885LMNA 2520/4885TSHR 209/4885 |
| US-20220056033-A1 | ADENOSINE RECEPTOR ANTAGONISTS AND USES THEREOF | ADORA2A, ADORA2B, ADORA3 | ALDH1A1 817/4885LMNA 2520/4885TSHR 209/4885 |
| US-11124515-B2 | Adenosine receptor antagonists and uses thereof | ADORA2B, ADORA2A, ADORA3 | ALDH1A1 634/4885LMNA 1901/4885TSHR 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.