Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130778 | 0.86 | L3MBTL1 (0.46) | LMNAPOLBTDP1MAPTALDH1A1 | |
| SCHEMBL9132673 | 0.85 | PLK1 (0.47) | LMNAPOLBTDP1MAPTALDH1A1 | |
| SCHEMBL9135710 | 0.85 | PLK1 (0.58) | LMNATDP1MAPTALDH1A1KMT2A | |
| SCHEMBL9132489 | 0.84 | PLK1 (0.60) | LMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9130744 | 0.84 | PLK1 (0.60) | LMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9129497 | 0.83 | LMNA (0.57) | LMNAPOLBTDP1MAPTALDH1A1 | |
| SCHEMBL9132519 | 0.83 | NR1H4 (0.53) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9130724 | 0.83 | PLK1 (0.46) | LMNAPOLBTDP1MAPTALDH1A1 | |
| SCHEMBL9132623 | 0.82 | MAPT (0.52) | LMNAPOLBTDP1MAPTALDH1A1 | |
| SCHEMBL9131404 | 0.82 | CYSLTR2 (0.44) | LMNAPOLBTDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399703-A | Antiallergens | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0536400-A1 | TETRAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-14 | — | — | EP | disclosed |