Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 4/20 | 0.60 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9132489 | 1.00 | PLK1 (0.60) | PLK1ACAT1NR1H4ALDH1A1LMNA | |
| SCHEMBL9135710 | 0.99 | PLK1 (0.58) | PLK1ACAT1NR1H4ALDH1A1LMNA | |
| SCHEMBL9132673 | 0.91 | PLK1 (0.47) | PLK1ACAT1ALDH1A1LMNAGAA | |
| SCHEMBL9134882 | 0.90 | ACAT1 (0.52) | PLK1ACAT1NR1H4ALDH1A1LMNA | |
| SCHEMBL9130724 | 0.89 | PLK1 (0.46) | PLK1ACAT1ALDH1A1LMNAGAA | |
| SCHEMBL9134929 | 0.89 | PLK1 (0.47) | PLK1ACAT1ALDH1A1LMNAGAA | |
| SCHEMBL9129998 | 0.87 | PLK1 (0.45) | PLK1ACAT1NR1H4ALDH1A1LMNA | |
| SCHEMBL9132519 | 0.87 | NR1H4 (0.53) | PLK1NR1H4SMN1; SMN2 | |
| SCHEMBL9131526 | 0.87 | L3MBTL1 (0.50) | PLK1ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL9130676 | 0.86 | CYSLTR2 (0.46) | PLK1ACAT1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399703-A | Antiallergens | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0536400-A1 | TETRAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-14 | — | — | EP | disclosed |