Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 6/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9135710 | 0.90 | PLK1 (0.58) | PLK1LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9132489 | 0.89 | PLK1 (0.60) | PLK1LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9130744 | 0.89 | PLK1 (0.60) | PLK1LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9132673 | 0.88 | PLK1 (0.47) | PLK1LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9134929 | 0.88 | PLK1 (0.47) | PLK1LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9129998 | 0.87 | PLK1 (0.45) | PLK1LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9132519 | 0.86 | NR1H4 (0.53) | PLK1SMN1; SMN2 | |
| SCHEMBL9131526 | 0.86 | L3MBTL1 (0.50) | PLK1LMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9129571 | 0.83 | LMNA (0.46) | LMNAALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL9130582 | 0.83 | CACNA1H (0.54) | PLK1GAABCHEACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399703-A | Antiallergens | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| EP-0536400-A1 | TETRAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-14 | — | — | EP | disclosed |