Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131759 | 0.88 | MAOA (0.51) | POLBMEN1MAPTKMT2ATDP1 | |
| SCHEMBL9133291 | 0.87 | KMT2A (0.53) | POLBMEN1MAPTKMT2ATDP1 | |
| SCHEMBL9296820 | 0.81 | MAPT (0.44) | POLBMEN1MAPTKMT2ATDP1 | |
| SCHEMBL9297964 | 0.78 | ADORA2A (0.50) | POLBMEN1MAPTKMT2ATDP1 | |
| SCHEMBL9130367 | 0.78 | ADORA2A (0.45) | POLBMEN1MAPTKMT2ATDP1 | |
| SCHEMBL9297405 | 0.77 | MAPT (0.46) | POLBMEN1MAPTKMT2ATDP1 | |
| SCHEMBL9297967 | 0.76 | BCL2 (0.51) | POLBMEN1MAPTKMT2ATDP1 | |
| SCHEMBL9131037 | 0.76 | MAPT (0.57) | POLBMEN1MAPTKMT2ATDP1 | |
| SCHEMBL9132901 | 0.76 | S100A4 (0.51) | POLBMEN1MAPTKMT2ATDP1 | |
| SCHEMBL9298054 | 0.76 | P4HB (0.45) | POLBMEN1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407885-A | Photochromic naphthacenequinones, process for their preparation and the use thereof | CIBA-GEIGY CORPORATION (US) | 1995-04-18 | — | — | US | disclosed |
| EP-0489689-B1 | Photochromic naphthacenequinones, process for their production and their use | CIBA GEIGY AG (CH) | 1995-03-01 | — | — | EP | disclosed |
| US-5208354-A | PHOTOCHROMIC NAPHTHACENEQUINONES, PROCESS FOR THEIR PREPARATION AND THE USE THEREOF | CIBA-GEIGY CORP. (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0489689-A1 | Photochromic naphthacenequinones, process for their production and their use | CIBA-GEIGY AG (CH) | 1992-06-10 | — | — | EP | disclosed |