Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | PTPRA | P18433 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357437 | 0.83 | HTT (0.53) | ALDH1A1HTTMAPK1TP53PKM | |
| Cystine SCHEMBL440076 | 0.80 | IDO1 (0.44) | ALDH1A1LMNAPOLBIDO1TDO2 | |
| SCHEMBL9130374 | 0.77 | HTT (0.40) | ALDH1A1HTTMAPK1TP53PKM | |
| Cysteine SCHEMBL9128017 | 0.74 | IDO1 (0.45) | ALDH1A1LMNAPOLBIDO1TDO2 | |
| SCHEMBL11197175 | 0.71 | CYP1A2 (0.55) | ALDH1A1MAPK1PKMLMNASLC1A5 | |
| SCHEMBL11197173 | 0.71 | CYP1A2 (0.55) | ALDH1A1MAPK1PKMLMNASLC1A5 | |
| Threonine SCHEMBL9838841 | 0.69 | USP2 (0.48) | ALDH1A1LMNAPOLBUSP2 | |
| Threonine SCHEMBL9838836 | 0.69 | USP2 (0.48) | ALDH1A1LMNAPOLBUSP2 | |
| SCHEMBL395878 | 0.67 | TDP1 (0.66) | ALDH1A1HTTKMT2ALMNAPOLB | |
| SCHEMBL31738422 | 0.67 | TDP1 (0.66) | ALDH1A1HTTKMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387673-A | Consisting of amino acids 70 to 155 of basic fibroblast growth factor; binds to heparin or heparin sepharose | AMERICAN CYANAMID COMPANY (US) | 1995-02-07 | — | — | US | disclosed |
| US-5206354-A | Shortest fragment that retains biological activity | AMERICAN CYANAMID COMPANY (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0486861-A1 | Active fragments of fibroblast growth factor | AMERICAN CYANAMID COMPANY (US) | 1992-05-27 | — | — | EP | disclosed |