Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128092 | 0.87 | ALDH1A1 (0.58) | LMNAMAPTALDH1A1ACHE | |
| SCHEMBL9129316 | 0.85 | ALDH1A1 (0.56) | MAPTALDH1A1ACHE | |
| SCHEMBL9126973 | 0.85 | ALDH1A1 (0.56) | MAPTALDH1A1ACHE | |
| SCHEMBL9131367 | 0.85 | LMNA (0.56) | LMNAMAPTALDH1A1ACHENPSR1 | |
| SCHEMBL9127891 | 0.80 | LMNA (0.49) | LMNAMAPTALDH1A1ACHEMTNR1A | |
| SCHEMBL6828889 | 0.80 | LMNA (0.60) | LMNAMAPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL20322895 | 0.80 | LMNA (0.60) | LMNAMAPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL9126486 | 0.79 | BCHE (0.53) | LMNAACHE | |
| SCHEMBL6240234 | 0.78 | LMNA (0.66) | LMNAMAPTALDH1A1NPSR1RXFP1 | |
| SCHEMBL23299733 | 0.77 | ALDH1A1 (0.57) | LMNAMAPTALDH1A1ACHENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401769-A | Anticholesterol | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-03-28 | — | — | US | claimed |
| US-5401769-A | Anticholesterol | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-03-28 | — | — | US | disclosed |