Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20322895 | 0.84 | LMNA (0.60) | LMNAMAOAMAPTALDH1A1NPSR1 | |
| SCHEMBL9131367 | 0.84 | LMNA (0.56) | LMNAMAOAMAPTALDH1A1NPSR1 | |
| SCHEMBL6240234 | 0.83 | LMNA (0.66) | LMNAMAOAMAPTALDH1A1NPSR1 | |
| SCHEMBL9130415 | 0.80 | LMNA (0.58) | LMNAMAOAMAPTALDH1A1NPSR1 | |
| SCHEMBL30137602 | 0.79 | MAOA (0.75) | LMNAMAOAHSD17B10MAPTALDH1A1 | |
| SCHEMBL5848964 | 0.79 | MAOA (0.75) | LMNAMAOAHSD17B10MAPTALDH1A1 | |
| SCHEMBL19077934 | 0.77 | NPC1 (0.55) | LMNAMAOAMAPTALDH1A1PTGER4 | |
| SCHEMBL17902702 | 0.77 | MAPT (0.59) | LMNAMAOAMAPTALDH1A1NPSR1 | |
| SCHEMBL9128092 | 0.76 | ALDH1A1 (0.58) | LMNAMAPTALDH1A1 | |
| Nitrogen SCHEMBL8500849 | 0.76 | MAOA (0.71) | LMNAMAOAHSD17B10MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740768-B1 | REACTING ALKYL OR ARYL ALCOHOL AND HALIDE WITH CARBON DIOXIDE AND CESIUM CARBONATE AT ROOM TEMPERATURE IN DIPOLAR APROTIC SOLVENT | GOEDECKE GMBH (DE) | 2004-05-25 | — | — | US | disclosed |