Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 10/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131226 | 0.88 | OPRD1 (0.71) | OPRK1OPRD1HSD11B1 | |
| SCHEMBL9127858 | 0.86 | OPRK1 (0.53) | OPRK1OPRD1MAPK1 | |
| SCHEMBL9127987 | 0.85 | OPRK1 (0.53) | OPRK1OPRD1HSD11B1 | |
| Hydrochloric Acid SCHEMBL8788611 | 0.84 | OPRD1 (0.76) | OPRK1OPRD1 | |
| SCHEMBL9129797 | 0.81 | OPRK1 (0.52) | OPRK1OPRD1 | |
| SCHEMBL9129660 | 0.81 | OPRK1 (0.48) | OPRK1 | |
| SCHEMBL9128011 | 0.74 | OPRD1 (0.66) | OPRK1OPRD1MAPK1 | |
| SCHEMBL9127069 | 0.73 | OPRD1 (0.65) | OPRK1OPRD1HSD11B1 | |
| SCHEMBL8722168 | 0.73 | ALDH1A1 (0.52) | OPRK1OPRD1MAPK1 | |
| SCHEMBL9373944 | 0.72 | OPRD1 (0.79) | OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472961-A | Acetamides | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-12-05 | — | — | US | disclosed |
| EP-0670318-A2 | Acetamides with analgesic and neuroprotective activity | MERCK PATENT GmbH (DE) | 1995-09-06 | — | — | EP | disclosed |